11/21/2023 0 Comments Free download dried plumsResearch focused on dietary strategies to optimize bone health and reduce life-long risk of osteoporotic fractures has resulted in the investigation of a wide range of foods and their bioactive components. These findings demonstrate that the CHO as well as the PP components of dried plum have potential prebiotic activity, but they have differential roles in mediating the alterations in bone formation and resorption that protect bone in estrogen deficiency. The PP and CHO components also altered the gut microbiota and cecal short chain fatty acids. Both the CHO and PP fractions of the extract contributed to the effects on bone with the CHO suppressing bone formation and resorption, and the PP temporally down-regulating formation. The effects of treatments on the bone phenotype were assessed at 5 and 10 weeks as well as the prebiotic activity of the different components of dried plum. Osteopenic ovariectomized mice were fed diets supplemented with dried plum, a crude extract of dried plum’s polyphenolic compounds, or the PP or CHO fraction of the crude extract. This study investigated the contribution of the fruit’s polyphenol (PP) and carbohydrate (CHO) components on a bone model of postmenopausal osteoporosis to explore their prebiotic activity. Evidence of dried plum’s benefits on bone continues to emerge.
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